JOB DESCRIPTION:

We are seeking a talented and highly-motivated Research Associate/Sr. Research Associate to join our collaborative discovery team to support small-molecule hit discovery using BlueLight Therapeutics’s proprietary technology for measuring protein structural changes. As a part of the team, they will play a central role in protein expression and purification, developing biochemical and biophysical assays and executing small-molecule screens for therapeutic targets. To join the dynamic, fast-paced, and venture-funded biotech team, the successful candidate will have a strong background in biochemistry with a demonstrated track record of success in protein biochemistry and/or assay development. The ideal candidate will be self-driven, resourceful, organized, and enjoy working in a dynamic team environment.

KEY RESPONSIBILITIES:

• Express, purify and label proteins to support assays to monitor structural changes in protein conformations

• In collaboration with the team, the S/RA will design, develop and execute screening assays including data analysis and interpretation

• Optimize screening assays to enable high-throughput screening (HTS)

• Support compound screening using BlueLight’s proprietary technology

• Communicate findings to the team including scientific presentations to the whole company

SKILLS & EXPERIENCE:

• BS or MS in Biochemistry, Biophysics, Molecular Biology or a related discipline is required. Prior experience in lab setting is required. 2 years of industry experience for RA and 5+ years for Sr RA is required (level and compensation commensurate with experience)

• Experience with recombinant protein expression and purification from E. coli is required.

• Prior experience in developing and running biochemical or biophysical plate-based assays (e.g., fluorescence or bioluminescence assays)

• Prior experience in small-molecule screening including familiarity with liquid handlers is preferred

• Excellent communication skills and ability to present key data, issues and accomplishments to other members of the team

• Good fit with BlueLight’s culture and values of highly collaborative, team-oriented work

OTHER INFORMATION:

• Full time employee at BlueLight Therapeutics, Inc.

• Located in South San Francisco

• Please submit resume or CVs to [email protected]