Research Associate/Sr Research Associate – Biochemistry


We are seeking a talented and highly-motivated Research Associate/Sr. Research Associate to join our collaborative discovery team to support small-molecule hit discovery using BlueLight Therapeutics’s proprietary technology for measuring protein structural changes. As a part of the team, they will play a central role in protein expression and purification, developing biochemical and biophysical assays and executing small-molecule screens for therapeutic targets. To join the dynamic, fast-paced, and venture-funded biotech team, the successful candidate will have a strong background in biochemistry with a demonstrated track record of success in protein biochemistry and/or assay development. The ideal candidate will be self-driven, resourceful, organized, and enjoy working in a dynamic team environment.


  • Express, purify and label proteins to support assays to monitor structural changes in protein conformations

  • In collaboration with the team, the S/RA will design, develop and execute screening assays including data analysis and interpretation

  • Optimize screening assays to enable high-throughput screening (HTS)

  • Support compound screening using BlueLight’s proprietary technology

  • Communicate findings to the team including scientific presentations to the whole company


  • BS or MS in Biochemistry, Biophysics, Molecular Biology or a related discipline is required. Prior experience in lab setting is required. 2 years of industry experience for RA and 5+ years for Sr RA is required (level and compensation commensurate with experience)

  • Experience with recombinant protein expression and purification from E. coli is required.

  • Prior experience in developing and running biochemical or biophysical plate-based assays (e.g., fluorescence or bioluminescence assays)

  • Prior experience in small-molecule screening including familiarity with liquid handlers is preferred

  • Excellent communication skills and ability to present key data, issues and accomplishments to other members of the team

  • Good fit with BlueLight’s culture and values of highly collaborative, team-oriented work


  • Full time employee at BlueLight Therapeutics, Inc.

  • Located in South San Francisco

  • Please submit resume or CVs to

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