Our Structure-Driven Platform

Our proprietary platform leverages Second Harmonic Generation (SHG) to measure structural changes of biomolecules in real time and with high throughput. Biomolecules undergo conformational changes that regulate activity and impact how they interact with other molecules in a pathway. By combining knowledge about a drug target’s native and disease-relevant biology with our platform, we can efficiently discover and develop molecules that induce functionally relevant structural changes in difficult-to-drug targets. Therefore, our drugs treat disease by inducing the desired conformational state in a key target.

  • Discover structure-modulating compounds missed by standard activity assays

  • Unearth novel and differentiated mechanisms of action

  • Develop drugs that induce desired conformational state in challenging targets

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Pipeline

Partnering

We are partnering with other biopharma to drive discovery and development of novel therapeutics for challenging targets.

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About us

BlueLight Therapeutics leverages a proprietary, structure-driven platform to develop novel therapeutic molecules against challenging, high-value drug targets. We have a passionate and experienced team with unique expertise on developing structural assays across a broad range of target classes.

Our investors include 5AM Ventures, Pfizer Ventures, and Alexandria Venture Investments. We are headquartered in South San Francisco, CA.

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Our News

  • JOBS

    Scientist/Sr Scientist – Biochemistry

    JOB DESCRIPTION: We are seeking a talented and highly-motivated Scientist/Sr. Scientist to join our collaborative discovery team to support small-molecule hit discovery using BlueLight Therapeutics’s proprietary technology for measuring protein structural changes. As a part of the team, they will play a central role in defining and executing on strategies to design small-molecule screening assays […]

  • JOBS

    Research Associate/Sr Research Associate – Biochemistry

    JOB DESCRIPTION: We are seeking a talented and highly-motivated Research Associate/Sr. Research Associate to join our collaborative discovery team to support small-molecule hit discovery using BlueLight Therapeutics’s proprietary technology for measuring protein structural changes. As a part of the team, they will play a central role in protein expression and purification, developing biochemical and biophysical […]

  • NEWS

    Biodesy Announces Corporate Name Change to BlueLight Therapeutics

    New company brand identity and Chief Scientific Officer appointment reflect long-term focus on developing small molecule therapeutics that regulate conformation of challenging drug targets   SOUTH SAN FRANCISCO, Calif. – May 27, 2020 – Biodesy Inc. today announced that it has changed its corporate name to BlueLight Therapeutics Inc., effective May 20, 2020, and appointed […]

Frequently Asked Questions

What is BlueLight Therapeutics?

BlueLight Therapeutics is a company focused on structure-driven drug discovery — using detailed molecular structure to guide the search for and design of new therapies. Call (650) 871-8716 to learn more.

What is structure-driven drug discovery?

It is an approach that uses the three-dimensional structure of biological targets to inform how potential drugs are identified and optimized, aiming to make discovery more precise.

Who does BlueLight work with?

As a drug-discovery company, BlueLight works in the research and pharmaceutical space. Call (650) 871-8716 to discuss collaboration or to learn more about the work.

How do I get in touch?

Call (650) 871-8716 or reach out through the site to connect with BlueLight Therapeutics.

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